Proteins in Response to Environmental Stress. UDP-glucuronosyltransferase.
نویسندگان
چکیده
منابع مشابه
Piscine UDP-glucuronosyltransferase 1B.
Glucuronidation is an important detoxification pathway for organic pollutants in fish. We report here the isolation and characterisation of UDP-glucuronosyltransferases (UGT) genes from the closely related marine flatfish, plaice (Pleuronectes platessa) and flounder (Platichthys flesus). The deduced amino acid sequences share greater similarity with mammalian UGT1 family genes than UGT2 genes (...
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The UDP-glucuronosyltransferase UGT2B7 is an important human UGT isoform that catalyzes the conjugation of many endogenous and exogenous compounds, among them opioids, resulting in the formation of D-glucuronides. The binding site of the aglycone is located in the N-terminal half of the protein. In this study, we demonstrate that the opioid binding site in UGT2B7 is within the first 119 amino-t...
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Effect of various NaCl treatments (0, 50, 100, 200, and 300 mM) at different growth and development stages (tillering, boot swellen, flowering and anthesis) in two wheat cultivars (Ghods: salt – sensitive, Boolani: salt – resistant) on SDS-PAGE electrophoretic pattern of leaf proteins was studied under greenhouse conditions. Generally, in response to salinity treatments, the decrease in protein...
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to determine the association between polymorphism of ugt1a1 gene and idiopathic hyperbilirubinemia in iranian neonates. fifty neonates with idiopathic hyperbilirubinemia and serum total bilirubin (stb) more that 15mg/dl and 50 neonates with idiopathic hyperbilirubinemia and serum total bilirubin (stb) less than 15mg/dl enrolled in this study. thymine-adenine (ta) repeats in the promoter region...
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Evolution depends on the manner in which genetic variation is translated into new phenotypes. There has been much debate about whether organisms might have specific mechanisms for "evolvability," which would generate heritable phenotypic variation with adaptive value and could act to enhance the rate of evolution. Capacitor systems, which allow the accumulation of cryptic genetic variation and ...
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ژورنال
عنوان ژورنال: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)
سال: 2002
ISSN: 0021-5082,1882-6482
DOI: 10.1265/jjh.56.629